Brian MacIsaac graduated from Natick High School in 2003.  He was an all-star receiver in football, a captain of the hockey team, and voted “most artistic” and “best personality” by his senior classmates.  During college at UMASS Dartmouth, he played guitar in a rock band, and studied digital media.  In April 2008, Brian was diagnosed with metastatic Ewing’s sarcoma, a rare pediatric bone cancer.

Despite the odds against him, Brian fought with grace and courage through 6 months of intense chemotherapy, until it stopped working.  He then entered a series of clinical drug trials hoping for a miracle, which never came.  Brian passed away at home surrounded by his family on April 8, 2009.  In his honor, his family and friends have created an IRS recognized charitable 501(c)(3) foundation in his name, to raise funds to fight this horrible disease.


The Brian MacIsaac Sarcoma Foundation was established May 6, 2010 to raise awareness of and to provide funding for sarcoma research, in particular Ewing’s sarcoma, and to help those confronting this terrible disease.  Brian became excited about fundraising and his family and friends are continuing his efforts.  The foundation is an IRS recognized 501 (c) (3) non profit organization and is registered with the Massachusetts Office of Attorney General Public Charities Division, and the Massachusetts Department of Revenue.